TRENAXA INJ
Tranexamic Acid(500.0 Mg/5ml)
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INTRODUCTION
TRENAXA INJECTION contains Tranexamic Acid which belongs to the group of medicines called Antifibrinolytics. It is used in the prevention and treatment of bleeding in conditions such as heavy menstrual bleeding in women, gastrointestinal bleeding (bleeding in digestive tract, anywhere from the throat to rectum), bleeding due to thrombolytic therapy (medicine that is used to breakdown blood clots) and after having surgeries (such as ear, nose, throat, prostate gland, urinary tract, gynecological, abdominal or heart surgery) in adults and children above one year of age.
TRENAXA INJECTION is not recommended for use in patients with severe kidney impairment, blood clotting disorder or consumption coagulopathy (condition affecting the blood’s ability to clot and stop the bleeding) or history of seizures (fits). Your doctor may recommend you to take relevant tests to understand your existing condition.
Before receiving TRENAXA INJECTION, inform your doctor if you had or have blood in the urine, are at risk of having a blood clot, excessive clotting or bleeding throughout the body (disseminated intravascular coagulation).
TRENAXA INJECTION is not recommended for use in the first trimester of pregnancy and in breast-feeding women. It should be used with caution in pregnant women only if clearly advised by the doctor. TRENAXA INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure.
The most common side effects of receiving TRENAXA INJECTION are nausea or vomiting and diarrhea. Inform your doctor immediately if any of the side effect worsens.
USES OF TRENAXA INJECTION
Prevent and treats bleeding in children (aged above one) and adults in conditions such as:
- heavy menstrual bleeding in women
- gastrointestinal bleeding
- after having surgeries (such as ear, nose, throat, heart, abdominal, gynaecological and prostrate or urinary tract surgery)
- bleeding due to medicine that is used to breakdown blood clots (thrombolytic therapy)
HOW TRENAXA INJECTION WORKS
TRENAXA INJECTION prevents bleeding by blocking the plasminogen from binding with fibrin which results in bleeding. As a result, it prevents and controls bleeding associated with various factors.
DIRECTIONS FOR USE
TRENAXA INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection. Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF TRENAXA INJECTION
COMMON
- diarrhea
- nausea, vomiting
UNCOMMON
- skin rashes
RARE
Inform your doctor immediately if you experience any of the following side effects while receiving TRENAXA INJECTION:
- severe allergic reaction (signs include redness of the skin and lumpy skin rashes, difficulty in breathing, swelling of face, mouth, lips or eyelids, unexplained high temperature (fever) and fainting)
- swelling of the throat that causes breathing and swallowing difficulty
- symptoms of a blood clot (such as swelling or pain in the legs or chest, headache, weakness of the face and limbs on one side of the body)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Inform your doctor if the symptom gets worse.
Nausea And Vomiting
Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedTRENAXA INJECTION is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if considered clearly necessary. Women of childbearing potential should use effective contraception during treatment with this medicine. Consult your doctor before receiving TRENAXA INJECTION.
BREASTFEEDING
ContraindicatedTRENAXA INJECTION is not recommended for use in breastfeeding women as it passes through breast milk. Consult your doctor for advice.
KIDNEY
Consult your doctorTRENAXA INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving TRENAXA INJECTION.
LIVER
Use with CautionTRENAXA INJECTION can be used with caution in patients with liver impairment. Consult your doctor before receiving TRENAXA INJECTION.
ALLERGY
ContraindicatedDo not receive TRENAXA INJECTION if you are allergic to Tranexamic acid or any other ingredients of this medicine.
USE IN PEDIATRICS
Use with CautionTRENAXA INJECTION should be used with caution in children above 1 year of age. Your child’s doctor will adjust the dose based on the bodyweight of the child. Consult child’s doctor for advice before administration of TRENAXA INJECTION.
USE IN GERIATRICS
Use with CautionTRENAXA INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor before receiving TRENAXA INJECTION.
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